Together with other iron compounds, ferrous sulfate is used to fortify foods and to treat iron-deficiency anemia.

It has been used in the purification of water by flocculation and for phosphate removal in municipal and industrial sewage treatment plants to prevent eutrophication of surface water bodies.

It is used as a traditional method of treating wood panelling on houses, either alone, dissolved in water, or as a component of water-based paint.

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